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A Highly Stereoselective, Efficient, and Scalable Synthesis of the C(1)-C(9) Fragment of the Epothilones. In five cases access was by an S- shaped incision, in one with a transposition flap. The local administration of simvastatin promotes the regeneration of an avascular meniscus in the rabbit model of a meniscal defect.
NMR and MALDI-TOF-MS analyses of the purified products revealed that GlcN-GlcNAc, (GlcN)2-GlcNAc, and (GlcN)2 were produced by the enzymatic digestion of the intact cells. To maximize the fidelity of DNA polymerases in the PCR, pH, concentrations of deoxynucleoside triphosphates, and magnesium ion were varied. Rosuvastatin disposition is modulated by the expression and activity of several membrane transporters including BCRP (ABCG2).
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